RE: [epilepsy] Uptick in Febrile Seizures Tied to Flu Vaccine

 

Uptick in Febrile Seizures Tied to Flu Vaccine

By Todd Neale, Staff Writer, MedPage Today
Published: January 20, 2011

<http://www.medpagetoday.com/ProductAlert/DevicesandVaccines/24449#rate>


The FDA and CDC have detected an increase in reports of febrile seizures
among children younger than 2 who received Fluzone, the trivalent
inactivated influenza vaccine made by Sanofi Pasteur.

Fluzone is the only vaccine recommended for use during the current flu
season in infants and children from 6 to 23 months of age.

The agencies are working together to investigate the connection, as well as
the possibility that other factors aside from influenza vaccination could be
involved, according to an FDA announcement.

The reports were submitted to the Vaccine Adverse Event Reporting System
(VAERS).

"Data from VAERS are preliminary and serve as a sign or indication that
further investigation is warranted," the FDA said.

In the meantime, the recommendation for vaccinating children against
influenza -- that everyone 6 months and older should be immunized -- remains
unchanged.

The FDA statement noted that all of the children with febrile seizure
recovered with no lasting effects and advised parents and caregivers to
speak with their children's healthcare providers about any questions or
concerns.

"Although febrile seizures can be frightening for the child's caregivers,
nearly all children who have a febrile seizure recover quickly and have no
long-term effects," the FDA stated.

VAERS data did not indicate an increase in febrile seizures in children
older than 2 following vaccination with trivalent inactivated vaccine or in
children who received live attenuated influenza vaccine.

A statement from Sanofi Pasteur said, "Reporting rates of febrile seizure
after administration of our influenza vaccine have been stable for years
even as distribution of the pediatric formulation has increased."

It continued, "Sanofi Pasteur is working closely with FDA in the
investigation of these events and will thoroughly assess all cases of
febrile seizure and any other adverse experiences reported following
administration of our vaccine."

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