Friday, March 26, 2010

[epilepsy] Nebulizing Magnesium and other Medicinals

 

This is a particularly good way to get magnesium and other medicinals into
babies and small children. Though I am not saying that it is not good for
adults too - it is and I know many people whom use it including my doctor
and many of her patients.
blessings
Shan

Nebulizing Magnesium and other Medicinals
_http://magnesiumforlife.com/transdermal-magnesium/nebulizing-magnesium-and-
other-medicinals/_
(http://magnesiumforlife.com/transdermal-magnesium/nebulizing-magnesium-and-other-medicinals/)


Sometimes very sick people or even animals with a lung ailment do better
when taking drugs by nebulization as opposed to orally, because then the
embattled system doesn't need to go through breaking down the medications in
the stomach and then delivering them to the lungs through the blood stream.
With nebulization medicines get sprayed directly onto the lung tissues
where they can most easily be absorbed locally by the lung and brachial cells.


Dr. Shallenberger says, "A nebulizer is able to convert a liquid into tiny
bubbles that are so tiny that they can only be seen under a microscope.
When these bubbles come out of the nebulizer, they are so small that they
look just like smoke. And that's the magic of a nebulizer. The bubbles are so
small that they can be inhaled deep down into the deepest regions of the
lungs without any discomfort or irritation. It's a great way for asthmatics
to get the medication they need to open up their lungs."


Few practitioners consider the systemic effects of nebulizers. When we
hear from patients using nebulizers with pharmaceuticals that it makes them
feel the side effects just as badly as when the doctors were giving the same
drug intravenously in the hospital, we are actually hearing that the
medicines are not only being delivered to the lungs but also being delivered
directly into the blood stream and systemically into the rest of the body.


This is very important to understand and appreciate because it opens a
wonderful delivery system that is important for certain populations like
infants, children, intensive care patients and to all those who are trying to
care for themselves or loved ones at home. And that's when Dr. Shallenberger
thought, "Why not use the nebulizer delivery system to deliver treatments
not just to the lungs but to the whole body?"


Most of the published research about nebulization is on standard usages
like asthma but this delivery system can be used to treat lung cancer,
pneumonia, tuberculosis, as well as the influenza, chemical poisoning, and
actually any syndrome requiring the administration of a medicinal. For
pediatricians and parents nebulizers are a God send because our babies cannot pop
pills and we don't really want to be sticking needles in them every day.
Transdermal medicine offers the most to the world of pediatrics with the
administration of medicines through their baths and their breathing.


The great strength of nebulizers though is their capability of delivering
medications and moisture directly to the tracheobronchial tree. Contrary to
other treatment options, higher concentrations in respiratory secretions
can be achieved with aerosol therapy. With the use of this localized
delivery system effective antimicrobials can have a direct effect on surface
organisms in the bronchial system.


1) Nebulization thins secretions & mucus making it easier to expel
pulmonary secretions
2) Nebulization makes coughing easier while lessening the need to cough
3) Nebulization keeps your windpipe & trachea lining and stoma moist &
healthy
4) Nebulization moistens the air that goes into your lungs
5) Nebulization hydrates & moisturizes your nasal passages, mouth and
throat


Nebulizers are good for young children, people who have trouble using
metered dose inhalers, and people who have severe asthma. Within 10 to 15
minutes, the medication is used up and symptoms are gone, or prevented for six
to eight hours. Even babies can breathe the mist and nebulizer treatments
are fast becoming pediatrician-approved alternatives to over-prescribed
antibiotics.


Several devices are available to create the drug aerosol particles. These
include jet nebulizers, ultrasonic nebulizers, metered-dose inhalers, and
dry powder inhalers through which particles can reach the upper and lower
respiratory tracts and be quickly absorbed into the bloodstream.


Aerosolized drugs have several advantages including quick onset of action
and low incidence of systemic adverse effects.[1] Delivery of aerosolized
medications typically does not cause pain to the patient, and it is
frequently a more convenient method of drug delivery. Studies show that the device
used really doesn't matter, as long as it's used properly. All methods
work just as well when the correct technique is used.[2] Nebulizing is
generally carried out for ten, twenty to thirty minutes each time and for best
results one may need to nebulize up to five times a day.


Transdermal medicine delivers medications
to the exact site of injury, pain or disease.


Transdermal medicine applied through a nebulizer is ideal for direct
treatment to the lungs. Transdermal methods of delivery are increasingly being
used because they allow the absorption of medicine directly through the
skin and in this case we conceptualize the lungs as an inner skin. Such
treatments ensure that medications reach the site of needed action directly;
bypassing the stomach and liver meaning a much greater percentage of the active
ingredient gets to target tissues.


At the Ohio State University Medical Center, pharmacists, respiratory
therapists, and pulmonologists endorse what they call off-label nebulization.
Off-label nebulization is a rapidly growing area of patient care and in time
new research and practical experience will bring us much more information
on how magnesium and other agents like sodium bicarbonate, iodine, peroxide
and glutathione can be administered directly into the lungs for many
difficult-to-treat conditions. Even DMSO has been used in veterinarian medicine
and naturopaths have used Tea Tree Oil from Australia, which is used
topically as fungicide antiseptic and germicide. Eucalyptus oil has also been
used forever because it is a known bronchial-dilator.


Nebulized Magnesium


Nebulization and Transdermal Medicinal Baths are Prime
Therapeutic Options for Medication Administration for Children


_Magnesium chloride oil_ (http://ancient-minerals.com/) should be
nebulized as an isotonic solution – delivering 7.5g magnesium chloride per 100ml
of distilled water – closely equal to 3.5 tsp of magnesium oil per 100ml.
Nebulization of magnesium is an alternative method of treatment for patients
with pulmonary problems or infections, or for those undergoing
bronchoscopy. Magnesium nebulized directly into the lungs offers all the same positive
therapeutic effects that other types of administration methods do but
concentrates the effects in the lung and bronchial tissues.


Nebulised inhaled magnesium sulfate in addition to 2-agonist in the
treatment of an acute asthma exacerbation, appears to have benefits with respect
to improved pulmonary function in patients with severe asthma.
Heterogeneity between trials included in this review precludes a more definitive
conclusion.[3] Nebulized magnesium is well tolerated without any adverse
effects.[4]


Currently, the most widely accepted treatments for asthma include
ß2-adrenergic agonists and corticosteroids. The search for treatment alternatives
for bronchoconstriction in acute asthma has led to the use of nebulized
magnesium.[5] Magnesium has been associated with cellular homeostasis and
frequently acts as a cofactor in enzymatic reactions. It has also been suggested
that magnesium acts as a smooth muscle relaxant by interfering with
calcium uptake. Research also suggests that magnesium may have a counteracting
effect against bronchoconstricting agents such as sodium metabisulfite,
methacholine, and histamine. Research into nebulized magnesium focuses on
treating asthma and the potential to counteract bronchoconstricting agents.


A randomized, double-blind, controlled clinical study compared nebulized
magnesium sulfate with nebulized albuterol in 33 patients with asthma (ages
12–60 years).[6] The study concluded that the serial doses of nebulized
magnesium sulfate had bronchodilatory effects similar to those noted with
nebulized albuterol.


Nannini et al.[7] examined magnesium sulfate as a vehicle for nebulized
albuterol in treating acute asthma. The authors concluded that when nebulized
magnesium and albuterol were used together, a higher peak flow could be
achieved in comparison to albuterol plus 0.9% sodium chloride. The
improvements could be seen within 10 minutes and lasted at least 20 minutes, and
patients suffering from the most severe airway obstruction had a greater
response to the combined treatment. Another study investigated the interactions
between magnesium sulfate and sodium metabisulfite, a common preservative in
food and drugs.[8] The investigators concluded that magnesium helped to
minimize the bronchoconstriction effects from sodium metabisulfite.


These studies strongly suggest that nebulized magnesium would be effective
for safe treatment of acute exacerbations of asthma, either as a sole
agent or in combination with other medications. For this application I
recommend only the _purest magnesium chloride_ (http://www.ancient-minerals.com/) .
. Even the pharmaceutical and higher grades have heavy metal contamination
so are not suitable.


Nebulized Bicarbonate


The bronchial secretions during attack of bronchial asthma are acidic and
the acidity imparts stickiness to the secretions and moreover there is high
level of neuraminic acid, which possibly correlates with the stickiness.
Thus sodium bicarbonate is an excellent choice for nebulization offering it'
s powerful and instant pH changing effects. Dr. Tullio Simoncini recommends
aerosol use of bicarbonate for lung and bronchial adenocarcinoma. He
recommends putting 1 soupspoon sodium bicarbonate in ½ liter water and inhaling
it with a fast inhaler in half an hour. Six days on six days off when in IV
break phases.


Dr. Lewis Nelson, a specialist in emergency medicine says, "Nebulized
sodium bicarbonate has been shown to provide symptomatic relief in patients
exposed to chlorine, and it is probably useful with all irritant gases that
liberate acid. Through a neutralization reaction, the damaging effects of the
acids are limited. Nebulized sodium bicarbonate should be used in
concentrations of less than 2% (which generally means about a 4:1 dilution of
standard 8% sodium bicarbonate)."[9]


Nebulized Peroxide


Hydrogen peroxide has been used for decades to conquer viral infections by
thousands of doctors in thousands of patients all over the world. Hydrogen
peroxide consists of a water molecule (H2O) with an extra oxygen atom
(H2O2). It is the extra oxygen atom that makes it so deadly for viruses.
Nebulization is a new way of administering hydrogen peroxide therapy that is
almost as effective as the IV. And better than the IV method, this new
treatment can be done at home, and is very inexpensive.


Nebulized peroxide is an efficient route of getting this oxygen utilizing
catalyst into the body via the rich network of blood vessels in the lungs.
This is not as strong a treatment as IV peroxide but it comes close.
Caution: Do not mix your own peroxide, this can be dangerous. If you feel bad
after the peroxide, with flu-like symptoms, headache, fever, diarrhea,
fatigue, etc, this is too strong a catalytic stimulation with peroxide. Consult
your physician before using peroxide in a nebulizer.


Dr. Shallenberger testimony: "When my wife developed the first symptoms of
flu, instead of immediately plugging her into a hydrogen peroxide IV, I
had her use the nebulizer for ten minutes every waking hour. Using the
nebulizer treatment, she was able to get rid of the flu within 72 hours. I knew I
was on to something, because IV hydrogen peroxide doesn't work much better
than that. So I bought a dozen nebulizers and began offering the treatment
to my patients."


"Since then I have treated hundreds of cases of colds, flus, sinusitis,
and bronchitis all with the same great results. And I found that the
nebulizer treatments actually have an advantage over the IV therapy that I hadn't
considered at first. And that is, that not only is the hydrogen peroxide
being disseminated into the entire body through the lungs, it is also going
directly to the areas of the body that are most affected by viruses – the
sinuses, throat, bronchial tract, and lungs."


Nebulized Iodine


In some countries nebulizers are given to people by prescription only
because they give a person direct access to the bloodstream and this is an
indication that this is serious medicine we are dealing with, so caution is
advised. With nebulizers we in part get the same effect as with injections,
medications quickly diffuse directly into the blood stream. Thus a nebulizer
holds the capacity to save lives.


When it comes to using iodine in a nebulizer special caution is needed.
The choice of iodine is important because putting in potassium, which is
found in Lugol's, is dangerous. Potassium chloride, another salt of potassium,
is used for lethal injection so I recommend only Nascent Iodine.
Nebulization with iodine offers an extremely strong therapy which can clear the
lungs quite rapidly of infections. Therapeutic concentrations can be increased
for desired effect but it is recommended that dosages start at the low end
unless there is an emergency situation. I would start my first iodine
treatment with a weak solution, 3 – 5 drops and slowly increase to ten drops or
more closely monitoring the experience. As long as the patient displays no
discomfort or side effects concentration can be increased strongly
especially when in a life threatening situation. One should expect much quicker and
more dramatic results with iodine then with H2O2.


Nebulized Glutathione


Glutathione has many profound roles in the body. One role is to enable the
liver to remove toxins, medications and other substances from the body.
Without it, these substances cannot be removed properly. One puts a special
small daily amount of glutathione in a nebulizer, which will facilitate
toxin removal and possibly tissue repair. The glutathione level of the
epithelial lining fluid is decreased in severe inflammatory lung diseases including
in cases with Cystic fibrosis.


Glutathione in the epithelial lining fluid (ELF) of the lower respiratory
tract is thought to be the first line of defense against oxidative stress.
Inhalation (nebulized or aerosolized) is the only known method that
increases GSH's levels in the ELF.[10]


Dr. Michelle Alpert, D.O says, "Because oral glutathione is not well
absorbed, I have also begun to experiment with nebulized glutathione, which
patients can take at home between detox drips. According to a study in
Alternative Medicine Review in 2000, nebulized glutathione has had remarkable
success in emphysema and other lung disorders such as asthma and bronchitis. It
appears that inhalation may have a systemic effect. Some patients are
having even greater success with this combination."[11]


In a case of a 95-year-old man with an acute respiratory crisis secondary
to emphysema and apparent bronchial infection treatment with nebulized
glutathione led to a rapid resolution of the crisis, as well as a marked
improvement in the chronic course of the disease. This treatment has been used
since for a number of patients with emphysema. The safety and bioavailability
of this method of delivery have been established in human studies.[12]


Different people taking Nebulized Glutathione often have very different
reactions. One person may tolerate Nebulized Glutathione well but not get the
desired effect, another may have side effects or adverse reactions that
make Nebulized Glutathione intolerable, and yet another may get the desired
effect with no side effects.[13]


General Instructions

Procedure: The basic aim of a nebulizer is to facilitate a faster and more
effective absorption of the medicine. This is achieved by breaking down
the liquid medicine into very fine particles, which is inhaled by the
patient. The first step is to add the liquid medicine to the cup attached to the
device. It is important to understand that these devices accept medicine in
the liquid form only, and medicine should be added at the time of usage and
not before that. If the doctor has prescribed more than one medicine for
nebulization, make sure if they can be mixed together or whether they should
be taken separately. Once the medicine is put in the cup, close the cup
and connect its tube to the air compressor. Turn the compressor on and when
the compressed air reaches the nebulizer cup, it will vaporize the medicine,
creating a mist. The mist is inhaled by the patient, through the
mouthpiece or face mask.


Take deep breaths and inhale the vapor completely. Tap the cup regularly
to ensure the right dispensation of medicine and don't remove the mask,
until the medicine is used up completely. It will take about 10 to 20 minutes
to finish nebulization depending on what type of medicinal is used. Turn on
the air pump and a mist will come from the mouthpiece. Place the mouthpiece
in your mouth and breathe in slowly. At full inhalation, hold your breath
for a 2-4 count to allow absorption in the lungs. If you are treating colds
or sinus problems, you can also alternate breathing through your nose.


Special Note: I have even heard of DMSO being used in combination with
other medicinals just as it would be used topically on the skin.


Online Purchasing Information

_http://www.outpatientmd.com/Nebulizers/_
(http://www.outpatientmd.com/Nebulizers/)

_http://www.outpatientmd.com/prodDetails.cfm?itemID=1229_
(http://www.outpatientmd.com/prodDetails.cfm?itemID=1229)

This second link is for a 30 dollar nebulizer with a five year guarantee.




Mark Sircus Ac., OMD
Director
International Medical Veritas Association
_http://publications.imva.info_ (http://publications.imva.info/)
Email: _director@naturalallopathic.com_
(mailto:director@naturalallopathic.com)

----------------------------------------------------------
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[1] Side effects wear off quickly but can include racing pulse, tremors,
nausea and insomnia. Nebulizer asthma treatments can also raise blood
pressure and aggravate glaucoma.

[2] _http://kidshealth.org/parent/medical/asthma/inhaler_nebulizer.html_
(http://kidshealth.org/parent/medical/asthma/inhaler_nebulizer.html)

[3] Inhaled magnesium sulfate in the treatment of acute asthma. Blitz M,
Blitz S, Beasely R, Diner BM, Hughes R, Knopp JA, Rowe BH

[4] Blitz M, et al. Inhaled magnesium sulfate in the treatment of acute
asthma. Cochrane Database Syst Rev 2005 Jul 20;(3) CD003898.

[5] Mahajan P, Haritos D, Rosenberg N et al. Comparison of nebulized
magnesium sulfate plus albuterol to nebulized albuterol plus saline in children
with acute exacerbations of mild to moderate asthma. J Emerg Med. 2004;
27:215.

[6] Mangat HS, D. Souza GA, Jacob MS. Nebulized magnesium sulphate versus
nebulized salbutamol in acute bronchial asthma, a clinical trial. Eur
Respir J. 1998; 12:3414.

[7] Nannini LJ, Pendino JC, Corna RA et al. Magnesium sulfate as a vehicle
for nebulized salbutamol in acute asthma. Am J Med. 2000; 108:193–7.

[8] Nannini LJ, Hofer D. Effect of inhaled magnesium sulfate on sodium
metabisulfite-induced bronchoconstriction in asthma. Chest. 1997; 111: 858–61.

[9] _http://www.emedmag.com/html/pre/tox/0804.asp_
(http://www.emedmag.com/html/pre/tox/0804.asp)

[10] _http://ecam.oxfordjournals.org/cgi/content/abstract/5/1/27_
(http://ecam.oxfordjournals.org/cgi/content/abstract/5/1/27)

[11] _http://www.prohealth.com/library/showarticle.cfm?libid=10906_
(http://www.prohealth.com/library/showarticle.cfm?libid=10906)

[12] Altern Med Rev 2000;5(5):429-431

[13] Reasons for inhaled GSH's effectiveness include its role as a potent
antioxidant, and possibly improved oxygenation and host defenses.
Theoretical uses of this treatment include Farmer's lung, pre- and postexercise,
multiple chemical sensitivity disorder and cigarette smoking. GSH inhalation
should not be used as a treatment for primary lung cancer. Testing for
sulfites in the urine is recommended prior to GSH inhalation. Minor side effects
such as transient coughing and an unpleasant odor are common with this
treatment. Major side effects such as bronchoconstriction have only occurred
among asthma patients presumed to be sulfite-sensitive. The potential
applications of inhaled GSH are numerous when one considers just how many
pulmonary diseases and respiratory-related conditions are affected by deficient
antioxidant status or an over production of oxidants, poor oxygenation and/or
impaired host defenses.

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