Wednesday, June 3, 2009

[epilepsy] Re: Bioavailability



I commend you on the time you spend on the Net; however; take exception to your asumptions and speculations about Pharmacists.

I, frankly, got a kick out of your remarks [to paraphrase] like a Pharmacist will switch from 1 generic company to another as they may be running deals.

Are you a Pharmacist?
I didn't think so.

Having established this....my Dad has been a Pharmacist for over 45 years.
Pharmacists only place their orders based on the store's volume and customer's needs.
They do not choose the vendor.
They are employees of the various nationwide drugstore companies.
Period.

And as far as brand name vs generic medications are concerned...most major insurance companies will only pay for generics. Oh yes, they may very well offer the option to purchase brand name, yet, as today's economy has sorely shown us time and again recently, many of us choose to stretch our dollar.

And most consumers are adept at perusing their prescriptions prior to submitting them...as well as checking their pill bottle[s] before they exit the store insuring they have paid for the correct product.

Finally... remember all meds sold via an Rx were approved by the high standards of the FDA.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

--- In epilepsy@yahoogroups.com, "Bruce M" <bruce903@...> wrote:
>
>
> With the help of topix.net, I came across an article, titled
> `Pharmacists may be switching your meds'
> <http://www.msnbc.msn.com/id/30627962/> . I don't know how long the
> article will remain online, so hopefully, for those of you who are
> reading this posting will be able to read the article.
>
> While reading over the article I started to remember a particular topic
> that was discussed during an epilepsy conference that I had attended
> several years ago. But I just could not remember a particular word that
> was used in that topic. So with the help of me taking notes during that
> epilepsy conference, and copying those notes to my computer, I was able
> to locate that particular word that I was trying to remember. And that
> word was, Bioavailability.
>
> The issue with generic medications is known as bioavailability, which is
> the amount of medication available for your body to absorb. The
> bioavailability of the medication has to be plus or minus a certain
> percentage of the bioavailability of the name brand drug. That
> "certain percentage" was something else I could not remember,
> but I did know that percentage had been increased by the FDA. So I did
> some online searching by using the word `bioavailability' and it
> appears that that certain percentage had been increased to roughly 20%.
>
> Now, for some people with epilepsy, but not everyone with epilepsy, that
> plus or minus 20% might not be such a big deal. However, for many of the
> other individuals who have epilepsy, and this does include people who
> might have their seizures controlled with brand-name antiepileptic
> medications, if the brand-name medication is switched over to a generic
> medication, the bioavailability of the medication could vary, and the
> person's blood level could very as well, which could result into
> problems either with toxicity or breakthrough seizures. Would you be
> willing to take the risk in order to find out if you, your loved one,
> and/or someone else you know who has epilepsy, might have these
> problems? I'm not.
>
> The generics can save you money, but the question is... "Where does
> your pharmacist get their generics?" Let's say for example, a
> pharmacist is getting low on one of their generic antiepileptic
> medications, and company `A' is having a special on their
> generic antiepileptic medications. Where's your pharmacist most likely
> going to get their generic antiepileptic medications? Yes, most likely
> from company `A'. Then later on, another company, company
> `C' comes in and says, "Listen, if you buy this much product
> from us, we'll give you and your spouse a free weekend in
> Hawaii." Where do you suppose your pharmacist is most likely going
> to get their generic antiepileptic medications this time? Yeah, company
> `C'. So do you suppose the bioavailability of company
> `A's' generic is going to be the same as the bioavailability
> of company `C's' generic? Probably not. One potential
> problem with generics is that pharmacists are probably not consistently
> buying from the same generic supplier.
>
> One advantage of brand-name drugs is you always know what you are
> getting. And to get these brand-name drugs, usually there are two lines
> on the physician's prescription pad. One says, `Dispense As
> Written' (DAW), which means the pharmacist has to fill the
> prescription exactly as the doctor has written it. Then there's another
> line that they can sign that says, `Substitutions Permitted',
> which means the pharmacist does not have to give you the name-brand
> drug. So if you're one of the individuals who needs or wants the
> brand-name drugs, then you want to make sure the prescription is signed
> by the physician on `Dispense as Written'.
>
> Going back to when I was searching online in order to find out what the
> results would be when using the word `bioavailability', the
> links I've included below are to a few websites that came up in the
> search results. And each of those 3 articles include the word and
> explanation for the word `bioequivalence'. I would highly
> recommend for everyone to read these articles because what is mentioned
> in them might be very helpful when dealing with generic antiepileptic
> medications, pharmacists, financial assistance, and or trying to
> maintain control, or a enough control, for your or someone else's
> seizures.
>
> Generic Drugs: They Save Money. But, Are They Effective and Safe?
> <http://www.originaldrugs.com/blog/general/brand-vs-generic-drugs/>
>
> The Epilepsy Battle in the War Between Brands and Generics
> <http://www.managedcaremag.com/archives/0803/0803.epilepsy.html>
>
> ... And just as a heads up, some of the words that are used in this next
> article, are not clean words.
>
> Brand Name Medications vs. Generic Drugs: The Differences Are Real.
> <http://www.crazymeds.us/BvsG.html>
>
>
>
> [Non-text portions of this message have been removed]
>

__._,_.___
Just a friendly reminder: Please remember to sign your post and remember to clean up messages when you reply to them.  This is especially important if you are on digest.  This not only helps out the list owner but, it makes messages much easier to read when they arrive in our inboxes.

Recent Activity
Visit Your Group
Yahoo! Groups

Auto Enthusiast Zone

Passionate about cars?

Check out the Auto Enthusiast Zone.

Health Groups

for people over 40

Join people who are

staying in shape.

Yahoo! Groups

Cat Owners Group

Join a community

for cat lovers

.

__,_._,___

No comments:

Post a Comment