About all I can say is "well, it's the Internet." If you look long enough, you can find a polarized view on everything. Extreme word choices like "lost every bit" of his muscle when fasting send up red flags for me. Clearly, that's just not true, since one could not breathe, swallow or move if one had lost every bit of muscle. I don't doubt the sincerity of his argument, but I can't find support for his facts. The author doesn't reference the study he calls on—one of his own, apparently, and he does not specify the animal involved, though from the masses given it was probably rats. I couldn't find the paper in PubMed. There's a decent summary about LPL in Wikipedia, which itself is no authority, but the references listed there support the Wikipedia content. For example, the 1992 paper by Braun and Severson states that "fasting results in a reduction in LPL activity in adipose tissue but an increase in cardiac tissue; as a result, fatty acids are diverted away from storage in adipose tissue to meet the metabolic demands of the heart under conditions of caloric deprivation." Basically, the body is doing what makes sense — freeing up the circulating fat where it's needed for fuel. When carbs are abundant and insulin is up, adipose LPL gets to work..so it's stored, which again makes sense. The window approach means your body stays in burn mode a lot longer than store mode, and is consistent with observed results — the fat gets burned instead of stored because insulin is usually low.
Given this data, I would think an LPL-based argument against IF would be that the window is too long or too frequent, since the shortest window possible should be ideal based on thinking only about lipoprotein lipase. There are other factors involved, of course, in defining a person's ideal approach to eating.
My explanation may not help much with your observation of a tendency to deposit carbs in fat stores. Our bodies probably have fat setpoints a little higher than we'd like because of genetic programming made to survive famines. That's okay based on insurance data that suggests a few pounds more than ideal is a healthier state than a few pounds below, but it doesn't match well with our preferences for a very lean physique.
It's my recollection that you bike to work and back. If so, are you still doing that? If you're not, your muscles' tendency to absorb what you eat into their built-in fat stores (what we call marbling in beef) may have decreased, allowing your adipose tissue to pick up more of what you eat. There may be long-term factors related to IF that no one is aware of yet because it has yet to be observed in the real world for the years or decades it may take for these sorts of things might come to light. I'm keeping an open mind, but on this count I'm not finding the argument legitimate based on the resources available.
I hope this helps,
Bert
On Jun 12, 2014, at 2:37 PM, no3rdseat@gmail.com [fast5] <fast5@yahoogroups.com> wrote:
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> Dr Herring-
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> I came across a video from a gentleman named Dr Gregory Ellis. He said he did his doctoral thesis on lipoprotein lipase and because of what he knows about it's role in metabolism, he recommends that people stay away from Warrior Diet type IF plans. He explains that lipoprotein lipase concentrates in the capillaries surrounding fat tissue and muscle tissue based on what you eat and how you eat. He says that when you fast all day and then eat within a short window, LpLi tends to accumulate in the capilaries around fat tissue which makes you tend to break down and store triglycerides in your fat, rather than breaking them down and using them for energy in your muscles. This is my understanding of what he says in the video. Do you agree witth this or is he wrong or is there more to the story?
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> Here's the link: Intermittent Fasting
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> Intermittent Fasting
> Intermittent fasting is a term used to describe changes in feeding/eating patterns. There are many possible variations in temporal patterns. Not onl...
> View on www.youtube.com
> Preview by Yahoo
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> I have to say, I've been on Fast-5 for nearly six years and I'm finding that even though I lift weights, everything I eat seems to go directly to my fat stores- especially if I eat anything carby like pies or bread.. I really do have to watch calories more and more.
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> Thanks
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> Rick Stewart
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Posted by: Bert Herring <bherring@fast-5.com>
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