Tammy,
I agree that generic AED's are very quick in entering the blood system.And,those
who use generics can't depend on these to be nearly as effective as name brand
medicines.So,don't depend on taking your doses at the same rate as you did with
the real thing.If name brands were taken twice daily it may be that a smaller
dose taken three times daily might work?Then just after getting use to it a
phamacy switchs from one manufacter to generics made by another company.But,I'd
stay with the real thing.With epilepsy we want long term treatment of the
AED.Not like where a drug being abused and people want to feel it in
their system as some as possible.
Tim Baldwin
________________________________
From: Tammara Wolfgram <tammy@maccetera.com>
To: epilepsy@yahoogroups.com
Sent: Sun, August 19, 2012 1:23:35 PM
Subject: [epilepsy] Re: Different generic
My understanding is that generics can also vary up to 10% in either direction in
terms of the active drug. While this wouldn't make a huge difference for most
conditions, it can well be the difference between having seizures and not having
seizures or of having overdose symptoms. For example, Megan was on 4000 mg of
Keppra. That would mean a generic could contain anywhere from 3600 mg to 4400 mg
for the same dose as the brand name drug. Also, the uptake into the blood stream
can be quite different for generics than their corresponding brand name drugs.
Megan was on generic Lamictal for a very short time. It was going into her
system more rapidly than the brand name drug, so she would have overdose
symptoms in the morning and was also likely to have a seizure before it was even
time for her evening dose.
Tammy
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